E3 ligase Ligand 27
E3 ligase Ligand 27 (part of 15) is a ligand for E3 ligase, used for the synthesis of PROTAC BcI-2/BcI-xI Degrader-1
Product Specifications
CAS Number
3034204-25-3
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-27.html
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)CCO4)C4=C2)=O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O
Molecular Formula
C28H38N4O6S
Molecular Weight
558.69
References & Citations
[1]Dongping, et al. Chimeric compound used for targeted degradation of bcl-2 protein, preparation method therefor, and pharmaceutical application thereof. Patent. WO2024067818A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Frequently Asked Questions
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