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LY-411575 (isomer 2)

LY-411575 isomer 2 is an isomer of LY411575, which is a potent γ-secretase inhibitor.

Product Specifications

CAS Number

[2070009-70-8]

UNSPSC

12352005

Target

γ-secretase

Type

Reference compound

Related Pathways

Neuronal Signaling; Stem Cell/Wnt

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly-411575-isomer-2.html

Purity

99.84

Solubility

10 mM in DMSO

Smiles

C[C@@H](NC([C@@H](O)C1=CC(F)=CC(F)=C1)=O)C(N[C@H](C(N2C)=O)C3=CC=CC=C3C4=C2C=CC=C4)=O

Molecular Formula

C26H23F2N3O4

Molecular Weight

479.48

References & Citations

[1]Fauq AH, et al. A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers. Bioorg Med Chem Lett. 2007 Nov 15;17 (22) :6392-5. Epub 2007 Aug 30.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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