LY-411575 (isomer 2)
LY-411575 isomer 2 is an isomer of LY411575, which is a potent γ-secretase inhibitor.
Product Specifications
CAS Number
[2070009-70-8]
UNSPSC
12352005
Target
γ-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-411575-isomer-2.html
Purity
99.84
Solubility
10 mM in DMSO
Smiles
C[C@@H](NC([C@@H](O)C1=CC(F)=CC(F)=C1)=O)C(N[C@H](C(N2C)=O)C3=CC=CC=C3C4=C2C=CC=C4)=O
Molecular Formula
C26H23F2N3O4
Molecular Weight
479.48
References & Citations
[1]Fauq AH, et al. A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers. Bioorg Med Chem Lett. 2007 Nov 15;17 (22) :6392-5. Epub 2007 Aug 30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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