Kremen-2, Cynomolgus (HEK293, His)

Kremen-2 protein is a receptor for Dickkopf protein and cooperates with DKK1/2 to inhibit Wnt/β-catenin signaling by promoting LRP5 and LRP6 endocytosis. Its role in limb development ensures correct patterning and negatively affects bone formation. Kremen-2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Kremen-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kremen-2 Protein, Cynomolgus (HEK293, His) is 339 a.a., with molecular weight of 50-65 kDa.