Me-IQ
Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].
Product Specifications
CAS Number
77094-11-2
Product Name Alternative
Methyl-IQ
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/me-iq.html
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3
Molecular Formula
C12H12N4
Molecular Weight
212.25
Precautions
H302, H315, H319, H335
References & Citations
[1]H Ohgaki, et al. Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp. 1985;16:97-105.|[2]T Aune, et al. Mutagenic activation of IQ and Me-IQ by liver and lung microsomes from rabbit and mouse, and with isolated lung cells from the rabbit. Carcinogenesis. 1986 Feb;7 (2) :273-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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