Me-IQ

Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].

Product Specifications

CAS Number

[77094-11-2]

Product Name Alternative

Methyl-IQ

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/me-iq.html

Purity

99.48

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3

Molecular Formula

C12H12N4

Molecular Weight

212.25

Precautions

H302, H315, H319, H335

References & Citations

[1]H Ohgaki, et al. Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp. 1985;16:97-105.|[2]T Aune, et al. Mutagenic activation of IQ and Me-IQ by liver and lung microsomes from rabbit and mouse, and with isolated lung cells from the rabbit. Carcinogenesis. 1986 Feb;7 (2) :273-6.