Recoflavone
Recoflavone (DA-6034 (free acid) ), a synthetic derivative of the flavonoid Eupatilin , is orally active. Recoflavone can inhibit the NF-κB pathway and induce [Ca (2+) ]i increase in epithelial cells. Recoflavone exhibits activities such as anti-inflammation, anti-tumor effects, protection of gastric and intestinal mucosa, and promotion of secretion in the ocular surface and salivary glands. Recoflavone can be used for the research of diseases such as dry eye, gastric injury, and intestinal injury[1][2][3][4].
Product Specifications
CAS Number
203191-10-0
Product Name Alternative
DA-6034 (free acid)
UNSPSC
12352005
Target
Apoptosis; Calcium Channel; COX; ERK; NF-κB
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/recoflavone.html
Purity
98.0
Solubility
DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=C2C(OC(C3=CC(OC)=C(OC)C=C3)=CC2=O)=CC(OCC(O)=O)=C1
Molecular Formula
C20H18O8
Molecular Weight
386.35
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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