Biotinylated Human IL-17C Protein, His, Avitag™ (MALS verified)
Interleukin-17C (IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
Product Specifications
Background
Specifications
Accession Number
Q9P0M4-1
Expression Region
His 19 - Val 197
Host
HEK293
Target
IL-17C
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Avi
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
PBS, 0.5 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
23.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q9P0M4-1
Preservative
Trehalose
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rat Activated Leukocyte Cell Adhesion Molecule, ALCAM ELISA Kit
Rat Activated Leukocyte Cell Adhesion Molecule, ALCAM ELISA Kit
