VKGILS-NH2 (TFA)
VKGILS-NH2 TFA is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist) . VKGILS-NH2 TFA has no effect on DNA synthesis in cells[1][2].
Product Specifications
CAS Number
2828432-41-1
UNSPSC
12352209
Target
Protease Activated Receptor (PAR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vkgils-nh2-tfa.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](CCCCN)NC([C@H](C(C)C)N)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Formula
C30H55F3N8O9
Molecular Weight
728.80
References & Citations
[1]M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131 (4) :689-94.|[2]David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293 (5) :F1441-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
PAR2
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