Amphiregulin Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha) . The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Abbreviation
Amphiregulin
UniProt
P15514
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Amphiregulin protein expressed by E.coli
Target
KAF; AREG; AR; AREGB; CRDGF; SDGF; amphiregulin; Colorectum Cell-Derived Growth Factor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IF
Field of Research
Signal Transduction; Cancer
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IF 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Isotype
IgG
Available Sizes
Documents
Curated Selection
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