P38-α MAPK-IN-7
P38-α MAPK-IN-7 (compound 4) is a p38α-MAPK inhibitor with an IC50 value of 98.7 nM. p38-α MAPK-IN-7 protects neuronal cells from dexamethasone-induced ROS production[1].
Product Specifications
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/p38-α-mapk-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1N=CN2N=C(SC3=CC=C(F)C=C3F)C=CC2=C1C4=C(Cl)C=C(N(C)CC#C)C=C4Cl
Molecular Formula
C23H14Cl2F2N4OS
Molecular Weight
503.35
References & Citations
[1]Claudia Albertini, et al. Targeting Lewy body dementia with neflamapimod-rasagiline hybrids. Arch Pharm (Weinheim) . 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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