AEOL-10150 (pentachloride)
Product Specifications
UNSPSC Description
AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant and is a superoxide dismutase mimetic, and protects lungs from radiation-induced injury[1].
Target Antigen
Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aeol-10150-pentachloride.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC[N+](C=CN1CC)=C1C2=C(C=CC3=C(C(N4CC)=[N+](C=C4)CC)C5=[N]6C(C=C5)=C7C(N8CC)=[N+](C=C8)CC)[N-]3[Mn+3]96[N]%10=C2C=CC%10=C(C(N%11CC)=[N+](C=C%11)CC)C%12=CC=C7[N-]9%12.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-]
Molecular Weight
1033.24
References & Citations
[1]Rabbani ZN, et al. Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury. Int J Radiat Oncol Biol Phys. 2007 Feb 1;67(2):573-80.|[2]Zhang XR, Zhou WX, Zhang YX. Improvements in SOD mimic AEOL-10150, a potent broad-spectrum antioxidant. Mil Med Res. 2018;5(1):30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19416/AEOL-10150-pentachloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19416/AEOL-10150-pentachloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
286475-30-7
Available Sizes
Curated Selection
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