Arachidonylcyclopropylamide
Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC50=2 nM) [1].
Product Specifications
CAS Number
[229021-64-1]
Product Name Alternative
ACPA
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/arachidonylcyclopropylamide.html
Concentration
145.54 mM * 100 μL in Ethanol
Purity
99.9
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1CC1)=O
Molecular Formula
C23H37NO
Molecular Weight
343.55
Precautions
H225, H319
References & Citations
[1]Franklin A, et al. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. Eur J Pharmacol. 2003;474 (2-3) :195-198.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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