Human BAFF Receptor (Recombinant)

<strong>Human BAFF Receptor</strong>_x000D_ <strong>Catalog number:</strong> B2010340_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human BAFF Receptor expressed in E. coli. This protein acts as a TNF Receptor that specifically interacts with BAFF._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuBAFF-R; CD268; TNFRSF13C; BR3_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Smulski CR, Eibel H. BAFF and BAFF-Receptor in B Cell Selection and Survival._x000D_ Front Immunol. 2018 Oct 8;9:2285._x000D_ _x000D_ 2: Dörner T, Posch MG, Li Y, Petricoul O, Cabanski M, Milojevic JM, Kamphausen_x000D_ E, Valentin MA, Simonett C, Mooney L, Hüser A, Gram H, Wagner FD, Oliver SJ._x000D_ Treatment of primary Sjögren's syndrome with ianalumab (VAY736) targeting B_x000D_ cells by BAFF receptor blockade coupled with enhanced, antibody-dependent_x000D_ cellular cytotoxicity. Ann Rheum Dis. 2019 May;78(5):641-647._x000D_ _x000D_ 3: Qin H, Wei G, Sakamaki I, Dong Z, Cheng WA, Smith DL, Wen F, Sun H, Kim K,_x000D_ Cha S, Bover L, Neelapu SS, Kwak LW. Novel BAFF-Receptor Antibody to Natively_x000D_ Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies_x000D_ <i>In Vivo</i>. Clin Cancer Res. 2018 Mar 1;24(5):1114-1123._x000D_ _x000D_ 4: Zheng N, Wang D, Ming H, Zhang H, Yu X. BAFF promotes proliferation of human_x000D_ mesangial cells through interaction with BAFF-R. BMC Nephrol. 2015 May 15;16:72._x000D_ _x000D_ 5: Croft M, Siegel RM. Beyond TNF: TNF superfamily cytokines as targets for the_x000D_ treatment of rheumatic diseases. Nat Rev Rheumatol. 2017 Apr;13(4):217-233._x000D_ _x000D_ 6: Qin H, Dong Z, Wang X, Cheng WA, Wen F, Xue W, Sun H, Walter M, Wei G, Smith_x000D_ DL, Sun X, Fei F, Xie J, Panagopoulou TI, Chen CW, Song JY, Aldoss I, Kayembe C,_x000D_ Sarno L, Müschen M, Inghirami GG, Forman SJ, Kwak LW. CAR T cells targeting_x000D_ BAFF-R can overcome CD19 antigen loss in B cell malignancies. Sci Transl Med._x000D_ 2019 Sep 25;11(511):eaaw9414._x000D_ _x000D_ 7: Shabgah AG, Shariati-Sarabi Z, Tavakkol-Afshari J, Mohammadi M. The role of_x000D_ BAFF and APRIL in rheumatoid arthritis. J Cell Physiol. 2019_x000D_ Aug;234(10):17050-17063._x000D_ _x000D_ 8: Gommerman JL, Rojas OL, Fritz JH. Re-thinking the functions of IgA(+) plasma_x000D_ cells. Gut Microbes. 2014;5(5):652-62._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25962322/">_x000D_ 9: Dickinson GS, Akkoyunlu M, Bram RJ, Alugupalli KR. BAFF receptor and TACI in_x000D_ B-1b cell maintenance and antibacterial responses. Ann N Y Acad Sci. 2015_x000D_ Dec;1362:57-67.</a>_x000D_ _x000D_ <strong>Products Related to Human BAFF Receptor </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>