CD11b Recombinant Rabbit Monoclonal Antibody [PSH03-96]
Selected Variant
HA722075
Size: 100 µL
Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ITGAM, CD11B, CR3A
Swiss Prot
P11215 Human, P05555 Mouse,
Cellular Locus
Cell membrane, Membrane raft.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CD11b aa 1-100.
Isotype
IgG
Clone
PSH03-96
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:5,000-1:20,000 ;IF-Tissue: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 127 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD22 / BL-CAM (B-Cell Marker) (BLCAM/1796), CF740 conjugate, 0.1mg/mL
Anti-NFkB/NFKB1 p105/p50 Antibody Picoband®, iFluor647 Conjugate
Anti-SDF2L1 Antibody Picoband® (Biotine Conjugate)
PAX8 (Renal Cell Marker) (PAX8/1492), CF640R conjugate, 0.1mg/mL
