(S,R,S)-AHPC-amido-C5-acid
Product Specifications
UNSPSC Description
(S,R,S)-AHPC-amido-C5-acid incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design XY028-133 (HY-129180)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-amido-c5-acid.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C[C@@H](C1)O)C([C@@H](NC(CCCCCC(O)=O)=O)C(C)(C)C)=O)NCC2=CC=C(C=C2)C3=C(N=CS3)C
Molecular Weight
572.72
References & Citations
[1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130798/S-R-S-AHPC-amido-C5-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130798/S-R-S-AHPC-amido-C5-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2162120-87-6
Available Sizes
Curated Selection
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