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Photoclick sphingosine

Photoclick sphingosine (Pacsph) is a photosensitizing and clickable sphingosine analog. Photoclick sphingosine is metabolized in cells into endogenous lipid metabolic pathways and can be visualized by its clickable alkyne group. Photoclick sphingosine can be used to study intracellular sphingolipid metabolism and subcellular localization[1].

Product Specifications

CAS Number

[1823021-14-2]

Product Name Alternative

Pacsph; Pacsphingosine (d18:1)

UNSPSC

12352005

Hazard Statement

H228, H315, H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/photoclick-sphingosine.html

Concentration

14.90 mM * 100 μL in Ethanol

Purity

99.0

Smiles

OC[C@H](N)[C@H](O)/C=C/CCCCCCCCC1(N=N1)CCCC#C

Molecular Formula

C19H33N3O2

Molecular Weight

335.48

Precautions

H228, H315, H319

References & Citations

[1]Hartwig P, et al., The Glucosylceramide Synthase Inhibitor PDMP Causes Lysosomal Lipid Accumulation and mTOR Inactivation. Int J Mol Sci. 2021 Jun 30;22 (13) :7065.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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