Moxidectin
Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk[1][2][3].
Product Specifications
CAS Number
113507-06-5
Product Name Alternative
CL301423
UNSPSC
12352005
Hazard Statement
H301
Target
Antibiotic; BCRP; Parasite; P-glycoprotein
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/moxidectin.html
Concentration
10mM
Purity
99.32
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
Molecular Formula
C37H53NO8
Molecular Weight
639.82
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Macrolide
Available Sizes
Frequently Asked Questions
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