MLS000536924
MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity[1].
Product Specifications
CAS Number
511306-37-9
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mls000536924.html
Smiles
CC1=CC=C(C=C1)CSC2=NN(C=N2)C3=CC=CC=C3
Molecular Formula
C16H15N3S
Molecular Weight
281.38
References & Citations
[1]Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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