LY377604
Product Specifications
UNSPSC Description
LY377604 is a human β3-adrenergic receptor agonist with an EC50 of 2.4 nM and also a β1- and β2-adrenergic receptor antagonist.
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/LY377604.html
Smiles
O=C(C1=CC=C(OC2=CC=C(CC(C)(NC[C@H](O)COC3=CC=CC(N4)=C3C5=C4C=CC=C5)C)C=C2)N=C1)N
Molecular Weight
524.61
References & Citations
[1]Jesudason CD, et al. Combination of a Beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesity. ACS Med Chem Lett. 2011 May 23;2(8):583-6.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13713/LY377604-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13713/LY377604-SDS-MedChemExpress.pdf
CAS Number
204592-94-9
Available Sizes
Curated Selection
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