Linoleic acid-d5

Linoleic Acid-d5 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2].

Product Specifications

CAS Number

[1169764-58-2]

UNSPSC

12352211

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Concentration

35.03 mM * 50 μL in Ethanol

Purity

99.77

Solubility

0.1 M NaOH : 8.33mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 60°C) |10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

Smiles

O=C(O)CCCCCCC/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]

Molecular Formula

C18H27D5O2

Molecular Weight

285.48

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4 (3) : 311–312.