Dimethyl succinate
Dimethyl succinate is an orally active cell permeable succinate analogue. Dimethyl succinate can disrupt the TCA cycle by elevating intracellular succinate levels, leading to reduced protein synthesis and impairs myogenic differentiation. Dimethyl succinate can induce apoptosis. Dimethyl succinate can decrease maximal cellular respiration and reserve capacity. Dimethyl succinate can rescue synapse loss in AD. Dimethyl succinate can be used for the researches of metabolic and neurological disease[1][2].
Product Specifications
CAS Number
[106-65-0]
UNSPSC
12352200
Hazard Statement
H319, H402
Target
Apoptosis
Type
Biochemical Assay Reagents
Related Pathways
Apoptosis
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dimethyl-succinate.html
Purity
99.95
Solubility
DMSO : 200 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C(OC)CCC(OC)=O
Molecular Formula
C6H10O4
Molecular Weight
146.14
Precautions
H319, H402
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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