Glycoborinine
Product Specifications
UNSPSC Description
Glycoborinine, a natural carbazole alkaloid, can be isolated from Glycosmis pentaphylla. Glycoborinine induces HepG2 cell apoptosis through mitochondrial pathway. Glycoborinine also inhibits HIV replication in cells[1][2].
Target Antigen
Apoptosis; HIV
Type
Natural Products
Related Pathways
Anti-infection;Apoptosis
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/glycoborinine.html
Solubility
10 mM in DMSO
Smiles
OC1=CC2=C(C=C1C)C3=C(C=CC4=C3C=CC(C)(C)O4)N2
Molecular Weight
279.33
References & Citations
[1]Yang H, et al. Glycoborinine induces apoptosis through mitochondrial pathway in HepG2 cells. J Asian Nat Prod Res. 2014 Oct;16(10):991-9.|[2]Yang JH, et al. Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation. Molecules. 2019 Dec 26;25(1):99.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N8361/Glycoborinine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N8361/
Clinical Information
No Development Reported
CAS Number
233279-39-5
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