Glycoborinine

Glycoborinine, a natural carbazole alkaloid, can be isolated from Glycosmis pentaphylla. Glycoborinine induces HepG2 cell apoptosis through mitochondrial pathway. Glycoborinine also inhibits HIV replication in cells[1][2].

Product Specifications

CAS Number

[233279-39-5]

UNSPSC

12352005

Target

Apoptosis; HIV

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/glycoborinine.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C(C=C1C)C3=C(C=CC4=C3C=CC(C)(C)O4)N2

Molecular Formula

C18H17NO2

Molecular Weight

279.33

References & Citations

[1]Yang H, et al. Glycoborinine induces apoptosis through mitochondrial pathway in HepG2 cells. J Asian Nat Prod Res. 2014 Oct;16 (10) :991-9.|[2]Yang JH, et al. Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation. Molecules. 2019 Dec 26;25 (1) :99.