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(2S,5S) -Censavudine

(2S,5S) -Censavudine ((2S,5S) -OBP-601) is the (2S,5S) -enantiomer of Censavudine. Censavudine, a nucleoside reverse transcriptase inhibitor, is a potent HIV inhibitor[1][2]. (2S,5S) -Censavudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

Product Name Alternative

(2S,5S) -Festinavir; (2S,5S) -BMS-986001; (2S,5S) -OBP-601

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2s-5s-censavudine.html

Purity

98.12

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C#C[C@]1(O[C@@](N(C=C2C)C(NC2=O)=O)([H])C=C1)CO

Molecular Formula

C12H12N2O4

Molecular Weight

248.24

References & Citations

[1]Robert A Smith, et al. The Nucleoside Analog BMS-986001 Shows Greater In Vitro Activity Against HIV-2 Than Against HIV-1. Antimicrob Agents Chemother. 2015 Dec;59 (12) :7437-46.|[2]Long Yuan, et al. Dried Blood Spot Analysis Without Dilution: Application to the LC-MS/MS Determination of BMS-986001 in Rat Dried Blood Spot. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:201-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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