NOTCH1, Mouse (HEK293, His)

NOTCH1 Protein acts as a receptor for membrane-bound ligands (JAG1, JAG2, and DLL1), determining cell fate.Upon activation, NICD forms a transcriptional activator complex, influencing differentiation, proliferation, and apoptosis.NOTCH1 negatively regulates angiogenesis, endothelial cell behavior, and impacts various developmental processes.It interacts with multiple partners, illustrating its involvement in signaling networks.NOTCH1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NOTCH1 protein, expressed by HEK293 , with C-6*His labeled tag.

AARGLRCSQP SGTCLNGGRC EVANGTEACV CSGAFVGQRC QDSNPCLSTP CKNAGTCHVV DHGGTVDYAC SCPLGFSGPL CLTPLDNACL ANPCRNGGTC DLLTLTEYKC RCPPGWSGKS CQQADPCASN PCANGGQCLP FESSYICRCP PGFHGPTCRQ DVNECSQNPG LCRHGGTCHN EIGSYRCACR ATHTGPHCEL PYVPCSPSPC QNGGTCRPTG DTTHECACLP GFAGQNCEEN VDDCPGNNCK NGGACVDGVN TYNCRCPPEW TGQYCTEDVD ECQLMPNACQ NGGTCHNTHG GYNCVCVNGW TGEDCSENID DCASAACFQG ATCHDRVASF YCECPHGRTG LLCHLNDACI SNPCNEGSNC DTNPVNGKAI CTCPSGYTGP ACSQDVDECA LGANPCEHAG KCLNTLGSFE CQCLQGYTGP RCEIDVNECI SNPCQNDATC LDQIGEFQCI CMPGYEGVYC EINTDECASS PCLHNGHCMD KINEFQCQCP KGFNGHLCQ