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Oxyphyllenone A

Oxyphyllenone A is an inhibitor of NO Synthase. Oxyphyllenone A inhibits the NO production in lipopolysaccharide-activated macrophages with an IC50 of 28 μM[1].

Product Specifications

CAS Number

[363610-34-8]

Product Name Alternative

(+) -Oxyphyllenone A

UNSPSC

12352211

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/oxyphyllenone-a.html

Solubility

10 mM in DMSO

Smiles

C[C@](CC1)(CC[C@H]2O)C([C@@](O)2C)=CC1=O

Molecular Formula

C12H18O3

Molecular Weight

210.27

References & Citations

[1]Muraoka O, et al. Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla. Bioorg Med Chem Lett. 2001 Aug 20;11 (16) :2217-20.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N9297/Oxyphyllenone-A-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N9297/

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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