Oxyphyllenone A
Oxyphyllenone A is an inhibitor of NO Synthase. Oxyphyllenone A inhibits the NO production in lipopolysaccharide-activated macrophages with an IC50 of 28 μM[1].
Product Specifications
CAS Number
[363610-34-8]
Product Name Alternative
(+) -Oxyphyllenone A
UNSPSC
12352211
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oxyphyllenone-a.html
Solubility
10 mM in DMSO
Smiles
C[C@](CC1)(CC[C@H]2O)C([C@@](O)2C)=CC1=O
Molecular Formula
C12H18O3
Molecular Weight
210.27
References & Citations
[1]Muraoka O, et al. Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla. Bioorg Med Chem Lett. 2001 Aug 20;11 (16) :2217-20.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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