Sodium-binding benzofuran isophthalate

SBFI is a cell-impermeant, fluorescent Na+ indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm[1]. SBFI selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [2].

Product Specifications

CAS Number

[124549-08-2]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sbfi.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C(C(O)=O)=C1)C2=CC3=CC(OC)=C(N4CCOCCOCCN(CCOCC4)C5=C(OC)C=C6C=C(C7=CC=C(C(O)=O)C=C7C(O)=O)OC6=C5)C=C3O2)O

Molecular Formula

C44H42N2O15

Molecular Weight

838.81

References & Citations

[1]Leeves MA, The effect of mechanical deformation on the distribution of ions in fibroblasts. Am J Orthod Dentofacial Orthop. 1995 Jun;107 (6) :625-32.|[2]Minta A, Fluorescent indicators for cytosolic sodium. J Biol Chem. 1989 Nov 15;264 (32) :19449-57.