Sigma-LIGAND-1
Sigma-LIGAND-1 is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor[1].
Product Specifications
CAS Number
[139652-01-0]
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4H-1-Benzopyran-4-one,_6-[[6-_4-hydroxy-1-piperidinyl_hexyl]oxy]-3-methyl-2-phenyl-.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13
Molecular Formula
C27H33NO4
Molecular Weight
435.56
References & Citations
[1]Erickson RH, et al. (Aminoalkoxy) chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35 (9) :1526-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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