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Multi-Leu peptide

Selected Variant

HY-P10422

Size: 1 Each

Multi-Leu peptide (ML-peptide) is a potent inhibitor of PACE4 (Ki=22 nM) . Multi-Leu peptide can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide can be used to study the specific mechanism of PACE4 in the development of prostate cancer[1].

Product Specifications

CAS Number

1413058-07-7

Product Name Alternative

ML-peptide, Multi-Leucine (ML) -peptide

UNSPSC

12352209

Target

Autophagy

Type

Peptides

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/multi-leu-peptide.html

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)C

Molecular Formula

C49H94N16O9

Molecular Weight

1051.37

References & Citations

[1]Łepek T, et al. Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations[J]. European journal of cell biology, 2017, 96 (5) : 476-485.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Price

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