Multi-Leu peptide
Multi-Leu peptide (ML-peptide) is a potent inhibitor of PACE4 (Ki=22 nM) . Multi-Leu peptide can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide can be used to study the specific mechanism of PACE4 in the development of prostate cancer[1].
Product Specifications
CAS Number
1413058-07-7
Product Name Alternative
ML-peptide, Multi-Leucine (ML) -peptide
UNSPSC
12352209
Target
Autophagy
Type
Peptides
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/multi-leu-peptide.html
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C49H94N16O9
Molecular Weight
1051.37
References & Citations
[1]Łepek T, et al. Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations[J]. European journal of cell biology, 2017, 96 (5) : 476-485.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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