Chimmitecan
Product Specifications
Product Name Alternative
Desmethyldoxepin (hydrochloride)
UNSPSC Description
Chimmitecan ((S)-9-Allyl-10-Hydroxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin (HY-16560), is a potent inhibitor of topoisomerase I. Chimmitecan exhibits anticancer activity[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/chimmitecan.html
Purity
98.96
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1[C@](CC)(C2=C(C(N3CC4=CC5=C(C(O)=CC=C5N=C4C3=C2)CC=C)=O)CO1)O
Molecular Weight
404.42
References & Citations
[1]Huang M, et, al. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin Cancer Res. 2007 Feb 15;13(4):1298-307.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114983/Chimmitecan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114983/Chimmitecan-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
185425-25-6
Available Sizes
Curated Selection
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