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Chimmitecan

Product Specifications

Product Name Alternative

Desmethyldoxepin (hydrochloride)

UNSPSC Description

Chimmitecan ((S)-9-Allyl-10-Hydroxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin (HY-16560), is a potent inhibitor of topoisomerase I. Chimmitecan exhibits anticancer activity[1].

Target Antigen

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/chimmitecan.html

Purity

98.96

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1[C@](CC)(C2=C(C(N3CC4=CC5=C(C(O)=CC=C5N=C4C3=C2)CC=C)=O)CO1)O

Molecular Weight

404.42

References & Citations

[1]Huang M, et, al. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin Cancer Res. 2007 Feb 15;13(4):1298-307.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114983/Chimmitecan-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114983/Chimmitecan-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

185425-25-6

Available Sizes

Curated Selection

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