Human Transforming Growth Factor β1

<strong>Human Transforming Growth Factor β1</strong>_x000D_ <strong>Catalog number:</strong> B2010333_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Transforming Growth Factor β1 expressed in CHO. This protein acts as a multifunctional cytokine which participates in foetal development, control of cell growth and differentiation._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> TGF-beta-1; TGFB1; TGFB; rHuTGF-β1_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lichtman MK, Otero-Vinas M, Falanga V. Transforming growth factor beta_x000D_ (TGF-β) isoforms in wound healing and fibrosis. Wound Repair Regen. 2016_x000D_ Mar;24(2):215-22._x000D_ _x000D_ 2: Lodyga M, Hinz B. TGF-β1 - A truly transforming growth factor in fibrosis and_x000D_ immunity. Semin Cell Dev Biol. 2020 May;101:123-139._x000D_ _x000D_ 3: Kim KK, Sheppard D, Chapman HA. TGF-β1 Signaling and Tissue Fibrosis. Cold_x000D_ Spring Harb Perspect Biol. 2018 Apr 2;10(4):a022293._x000D_ _x000D_ 4: Kudva AK, Dikina AD, Luyten FP, Alsberg E, Patterson J. Gelatin microspheres_x000D_ releasing transforming growth factor drive in vitro chondrogenesis of human_x000D_ periosteum derived cells in micromass culture. Acta Biomater. 2019_x000D_ May;90:287-299._x000D_ _x000D_ 5: Hinz B. The extracellular matrix and transforming growth factor-β1: Tale of a_x000D_ strained relationship. Matrix Biol. 2015 Sep;47:54-65._x000D_ _x000D_ 6: Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β_x000D_ structure and activation. Nature. 2011 Jun 15;474(7351):343-9._x000D_ _x000D_ 7: Tarbit E, Singh I, Peart JN, Rose'Meyer RB. Biomarkers for the identification_x000D_ of cardiac fibroblast and myofibroblast cells. Heart Fail Rev. 2019_x000D_ Jan;24(1):1-15._x000D_ _x000D_ 8: Wattanapakkavong K, Srisuwan T. Release of Transforming Growth Factor Beta 1_x000D_ from Human Tooth Dentin after Application of Either ProRoot MTA or Biodentine as_x000D_ a Coronal Barrier. J Endod. 2019 Jun;45(6):701-705._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/28035727/">9: Delaney K, Kasprzycka P, Ciemerych MA, Zimowska M. The role of TGF-β1 during_x000D_ skeletal muscle regeneration. Cell Biol Int. 2017 Jul;41(7):706-715. </a>_x000D_ _x000D_ <strong>Products Related to Human Transforming Growth Factor β1 </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>