(±) -Stylopine (hydrochloride)

(±) -Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities[1][2].

Product Specifications

CAS Number

[96087-21-7]

Product Name Alternative

Tetrahydrocoptisine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H301-H311-H331

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/racemic-stylopine-hydrochloride.html

Purity

99.66

Solubility

DMSO : 2 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

[H]Cl.C1(C(CCN2CC3=C4OCOC4=CC=C3CC21)=C5)=CC6=C5OCO6

Molecular Formula

C19H18ClNO4

Molecular Weight

359.80

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Li W, et al. Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAP|[2]Li W, et al. Protective effect of tetrahydrocoptisine against ethanol-induced gastric ulcer in mice. Toxicol Appl Pharmacol. 2013 Oct 1;272 (1) :21-9.