LH-RH (4-10)
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes[1].
Product Specifications
CAS Number
51776-33-1
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/lh-rh-4-10.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@@H](N)CO)=O)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(NCC(N)=O)=O)=O)=O)=O)=O
Molecular Formula
C33H53N11O9
Molecular Weight
747.84
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Yang X, et al. Enzymatic degradation of luteinizing hormone releasing hormone (LHRH) /[D-Ala6]-LHRH in lung pneumocytes. Pharm Res. 1998 Sep;15 (9) :1480-4. |[2]Talwar GP, et al. Bioeffective monoclonal antibody against the decapeptide gonadotropin-releasing hormone: reacting determinant and action on ovulation and estrus suppression. Proc Natl Acad Sci U S A. 1985 Feb;82 (4) :1228-31.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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