Aniline mustard
Aniline mustard (N, n-BIS (2-chloroethyl) aniline) is an anticancer agent[1].
Product Specifications
CAS Number
553-27-5
Product Name Alternative
N, N-Bis (2-chloroethyl) aniline
UNSPSC
12352005
Hazard Statement
H314
Target
Apoptosis; Caspase; DNA/RNA Synthesis; Mitochondrial Metabolism; PARP; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aniline-mustard.html
Purity
99.90
Solubility
DMSO : ≥ 100 mg/mL
Smiles
ClCCN(C1=CC=CC=C1)CCCl
Molecular Formula
C10H13Cl2N
Molecular Weight
218.13
Precautions
H314
References & Citations
[1]Fedeles BI, et al. Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target. J Biol Chem. 2011;286 (39) :33910-33920.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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