Alilusem (potassium)
Alilusem potassium is a diuretic. In anesthetized dogs undergoing water diuresis, Alilusem potassium effectively decreased free water clearance and increased Na+ and Cl- levels in excreted urine. When combined with Furosemide (HY-B0135) or Hydrochlorothiazid, Alilusem potassium further inhibited free water clearance. Alilusem potassium inhibited the lumen-positive transepithelial voltage and lumen-to-cistern Cl- flux in isolated rabbit cortical thick ascending limbs of Henle[1].
Product Specifications
CAS Number
[114417-20-8]
Product Name Alternative
M 17055
UNSPSC
12352005
Target
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/alilusem-potassium.html
Smiles
O=C(C1=CC=CC=C1C)N2CC/C(C3=C2C=C(C=C3)Cl)=N\OS(=O)(O[K])=O
Molecular Formula
C17H14ClKN2O5S
Molecular Weight
432.92
References & Citations
[1]Loop and distal actions of a novel diuretic, M17055
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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