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Pilabactam (sodium)

Pilabactam (ANT3310) sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase) . Pilabactam sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB) . Pilabactam sodium can be used in the research of bacterial infection[1][2].

Product Specifications

CAS Number

2410688-61-6

Product Name Alternative

ANT3310 (sodium)

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ant3310-sodium.html

Concentration

10mM

Purity

99.54

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(ON1[C@H]2C[N@]([C@@H](CC2)F)C1=O)(O[Na])=O

Molecular Formula

C6H8FN2NaO5S

Molecular Weight

262.19

References & Citations

[1]David T Davies, et al. Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii. J Med Chem. 2020 Dec 24;63 (24) :15802-15820.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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