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STAT3 HiBiT degrader 1

STAT3 HiBiT degrader 1 is a STAT3 HiBiT degrader with a DC50 of less than 0.05 μM in A549 cells[1].

Product Specifications

CAS Number

2767166-30-1

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/stat3-hibit-degrader-1.html

Smiles

FC(F)(P(O)(O)=O)C1=CC(C=C(C(N[C@H]2CN(C(OC)=O)CC[C@@H]3N([C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N4CCC(CCC#CC5=CC(N(C)C(N6C7C(NC(CC7)=O)=O)=O)=C6C=C5)CC4)=O)CC8=CC=C(F)C(F)=C8)=O)=O)CC3)C2=O)=O)S9)=C9C=C1

Molecular Formula

C58H63F4N10O14PS

Molecular Weight

1263.21

References & Citations

[1]Bin Yang, et al. Stat degraders and uses thereof. US. US20240293423A1. 2021.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

STAT3

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