CD137 antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Synonyms
Tumor necrosis factor receptor superfamily member 9|4-1BB ligand receptor|CDw137|T-cell antigen 4-1BB homolog|T-cell antigen ILA|TNFRSF9|CD137|ILA
Gene ID
3604
UniProt
Q07011
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tumor necrosis factor receptor superfamily member 9
Target
CD137
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
27 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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