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MDL 105519

MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor.

Product Specifications

CAS Number

161230-88-2

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/MDL-105519.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : 17 mg/mL (ultrasonic; warming)

Smiles

O=C(O)C(N1)=C(/C=C(C2=CC=CC=C2)/C(O)=O)C3=C1C=C(Cl)C=C3Cl

Molecular Formula

C18H11Cl2NO4

Molecular Weight

376.19

References & Citations

[1]Baron BM, et al. Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist. Eur J Pharmacol. 1997 Apr 4;323 (2-3) :181-92.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Available Sizes

Frequently Asked Questions

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