MDL 105519
MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor.
Product Specifications
CAS Number
[161230-88-2]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MDL-105519.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 17 mg/mL (ultrasonic; warming)
Smiles
O=C(O)C(N1)=C(/C=C(C2=CC=CC=C2)/C(O)=O)C3=C1C=C(Cl)C=C3Cl
Molecular Formula
C18H11Cl2NO4
Molecular Weight
376.19
References & Citations
[1]Baron BM, et al. Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist. Eur J Pharmacol. 1997 Apr 4;323 (2-3) :181-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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