Hedgehog agonist 1
Hh agonist 1 (compound 21k) is a potent Hedgehog (Hh) agonist, with an EC50 0.3 nM. Hh agonist 1 can be used for the research of stroke and other neurological disorders[1].
Product Specifications
CAS Number
946002-48-8
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hedgehog-agonist-1.html
Purity
99.83
Solubility
DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(Cl)C2=C(F)C=CC(F)=C2S1)N(CC3=CC(C4=CC=NC=C4)=CC=C3OC)[C@H]5CC[C@H](NC)CC5
Molecular Formula
C29H28ClF2N3O2S
Molecular Weight
556.07
References & Citations
[1]Brunton SA, et al. Potent agonists of the Hedgehog signaling pathway. Bioorg Med Chem Lett. 2009 Aug 1;19 (15) :4308-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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