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Hedgehog agonist 1

Hh agonist 1 (compound 21k) is a potent Hedgehog (Hh) agonist, with an EC50 0.3 nM. Hh agonist 1 can be used for the research of stroke and other neurological disorders[1].

Product Specifications

CAS Number

946002-48-8

UNSPSC

12352005

Target

Hedgehog

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hedgehog-agonist-1.html

Purity

99.83

Solubility

DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=C(Cl)C2=C(F)C=CC(F)=C2S1)N(CC3=CC(C4=CC=NC=C4)=CC=C3OC)[C@H]5CC[C@H](NC)CC5

Molecular Formula

C29H28ClF2N3O2S

Molecular Weight

556.07

References & Citations

[1]Brunton SA, et al. Potent agonists of the Hedgehog signaling pathway. Bioorg Med Chem Lett. 2009 Aug 1;19 (15) :4308-11.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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