MX106-4C
Product Specifications
UNSPSC Description
MX106-4C is a survivin inhibitor that selectively kills ABCB1-positive colorectal cancer cells. MX106-4C can exert synergistic anticancer effects with Doxorubicin or resensitize drug-resistant ABCB1 cells to Doxorubicin[1].
Target Antigen
Survivin
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/mx106-4c.html
Solubility
DMSO : 8 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC1=C(CN2CCCC2)C=C(COCC3=CC=C(C)C=C3Br)C4=CC=CN=C41
Molecular Weight
441.36
References & Citations
[1]Lei ZN, et al. ABCB1-dependent collateral sensitivity of multidrug-resistant colorectal cancer cells to the survivin inhibitor MX106-4C. Drug Resist Updat. 2024 Mar;73:101065.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162324/MX106-4C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162324/MX106-4C-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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