Bronopol
Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria) . Bronopol oxidizes protein thiols, inhibits enzymatic activity, and exhibits antibacterial activity. Bronopol is also a formaldehyde releaser[2][3].
Product Specifications
CAS Number
52-51-7
Product Name Alternative
BNPD; BNPK
UNSPSC
12352211
Hazard Statement
H302, H312, H315, H318, H335, H400, H410
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Bronopol.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OCC([N+]([O-])=O)(Br)CO
Molecular Formula
C3H6BrNO4
Molecular Weight
199.99
Precautions
H302, H312, H315, H318, H335, H400, H410
References & Citations
[1]Shepherd JA, et al. Antibacterial action of 2-bromo-2-nitropropane-1,3-diol (bronopol) . Antimicrob Agents Chemother. 1988 Nov;32 (11) :1693-8.|[2]Kireche M, et al., Evidence for chemical and cellular reactivities of the formaldehyde releaser bronopol, independent of formaldehyde release. Chem Res Toxicol. 2011 Dec 19;24 (12) :2115-28.|[3]Nieminen L, et al., The pain aggression induced by bronopol in the rat. Acta Pharmacol Toxicol (Copenh) . 1975 Sep;37 (3) :237-41.|[4]Bryce D M, et al. The activity and safety of the antimicrobial agent bronopol (2-bromo-2-nitropropan-1, 3-diol) [J]. J. Soc. Cosmet. Chem, 1978, 29: 3-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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