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Ganglioside GM1 (bovine) (ammonium)

Selected Variant

HY-N10546A-01

Size: 1 mg

Ganglioside GM1 (bovine) ammonium is a type of glycosphingolipid, mainly found on the cell membranes of the central nervous system of vertebrates. Ganglioside GM1 (bovine) ammonium exerts neuroprotective effects by reducing excessive activation of NMDAR, activating TrkA and ERK1/2, and inhibiting oxidative stress and cell apoptosis and autophagy. Ganglioside GM1 (bovine) ammonium can be used in the research of diseases such as traumatic brain injury, Parkinson's disease, Alzheimer's disease, and Huntington's disease[1][2][3].

Product Specifications

CAS Number

1007119-81-4

UNSPSC

12352211

Target

Apoptosis; Autophagy; ERK; iGluR; Trk Receptor

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ganglioside-gm1-bovine-ammonium.html

Purity

98.0

Smiles

[GangliosideGM1(bovine)(ammonium)]

References & Citations

[1]Wenchao Zhang, et al. Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review. Cell Transplant. 2019 Jun;28 (6) :657-661. |[2]Chiricozzi E, et al. GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration. Int J Mol Sci. 2020 Jan 29;21 (3) :868.|[3]Guo Z. Ganglioside GM1 and the Central Nervous System. Int J Mol Sci. 2023 May 31;24 (11) :9558.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Price

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