PPL-100 (free acid)

PPL-100 free acid is a potential agent for SERPINA1. PPL-100 free acid can be metabolically cleaved into PL-100 (HY-107468) [1][2].

Product Specifications

CAS Number

[874339-65-8]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ppl-100-free-acid.html

Smiles

CC(CN(S(=O)(C1=CC=C(N)C=C1)=O)[C@H](COP(O)(O)=O)CCCCNC([C@@H](NC(OC)=O)C(C2=CC=CC=C2)C3=CC=CC=C3)=O)C

Molecular Formula

C33H45N4O9PS

Molecular Weight

704.77

References & Citations

[1]Dandache S, et, al. PL-100, a novel HIV-1 protease inhibitor displaying a high genetic barrier to resistance: an in vitro selection study. J Med Virol. 2008 Dec;80 (12) :2053-63. |[2]Qu T, et, al. Identification of potential biomarkers and drugs for papillary thyroid cancer based on gene expression profile analysis. Mol Med Rep. 2016 Dec;14 (6) :5041-5048.