PPL-100 (free acid)
PPL-100 free acid is a potential agent for SERPINA1. PPL-100 free acid can be metabolically cleaved into PL-100 (HY-107468) [1][2].
Product Specifications
CAS Number
[874339-65-8]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ppl-100-free-acid.html
Smiles
CC(CN(S(=O)(C1=CC=C(N)C=C1)=O)[C@H](COP(O)(O)=O)CCCCNC([C@@H](NC(OC)=O)C(C2=CC=CC=C2)C3=CC=CC=C3)=O)C
Molecular Formula
C33H45N4O9PS
Molecular Weight
704.77
References & Citations
[1]Dandache S, et, al. PL-100, a novel HIV-1 protease inhibitor displaying a high genetic barrier to resistance: an in vitro selection study. J Med Virol. 2008 Dec;80 (12) :2053-63. |[2]Qu T, et, al. Identification of potential biomarkers and drugs for papillary thyroid cancer based on gene expression profile analysis. Mol Med Rep. 2016 Dec;14 (6) :5041-5048.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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