17α-Hydroxyprogesterone acetate

17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2].

Product Specifications

CAS Number

[302-23-8]

UNSPSC

12352211

Hazard Statement

H351

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/17α-hydroxyprogesterone-acetate.html

Purity

99.75

Solubility

DMSO : 5.71 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O

Molecular Formula

C23H32O4

Molecular Weight

372.50

Precautions

H351

References & Citations

[1]R E Seegmiller, et al. Evaluation of the teratogenic potential of delalutin (17 alpha-hydroxyprogesterone caproate) in mice. Teratology. 1983 Oct;28 (2) :201-8.|[2]Amy-Eunice Furcron, et al. Vaginal progesterone, but not 17α-hydroxyprogesterone caproate, has antiinflammatory effects at the murine maternal-fetal interface. Am J Obstet Gynecol. 2015 Dec;213 (6) :846.e1-846.e19.