Pyrimidine Nucleoside Phosphorylase

<strong>Pyrimidine Nucleoside Phosphorylase</strong>_x000D_ <strong>Catalog number:</strong> B2017876_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nwosu ZC, Ward MH, Sajjakulnukit P, Poudel P, Ragulan C, Kasperek S, Radyk M, Sutton D, Menjivar RE, Andren A, Apiz-Saab JJ, Tolstyka Z, Brown K, Lee HJ, Dzierozynski LN, He X, Ps H, Ugras J, Nyamundanda G, Zhang L, Halbrook CJ, Carpenter ES, Shi J, Shriver LP, Patti GJ, Muir A, Pasca di Magliano M, Sadanandam A, Lyssiotis CA. Uridine-derived ribose fuels glucose-restricted pancreatic cancer Nature. 2023 Jun;618(7963):151-158._x000D_ 2: Kaspar F, Neubauer P, Kurreck A. The Peculiar Case of the Hyper-thermostable Pyrimidine Nucleoside Phosphorylase from Thermus thermophilus* Chembiochem. 2021 Apr 16;22(8):1385-1390._x000D_ 3: Wen Y, Li X, Guo W, Wu B. Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold Proteins. 2022 Jun;90(6):1233-1241._x000D_ 4: Vande Voorde J, Liekens S, Gago F, Balzarini J. The pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis and how it may affect nucleoside-based therapy Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):394-402._x000D_ 5: Balaev VV, Prokofev II, Gabdoulkhakov AG, Betzel C, Lashkov AA. Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate Acta Crystallogr F Struct Biol Commun. 2018 Apr 1;74(Pt 4):193-197._x000D_ 6: Liu K, Zhou Y, Zhang J, Chu J, Zhang Y, He B. A thermostable pyrimidine_nucleoside phosphorylase from Brevibacillus borstelensis LK01 for synthesizing halogenated nucleosides Biotechnol Lett. 2017 Dec;39(12):1903-1910._x000D_ 7: Higley B, Oakes J, De Mello J, Giles GR. Pyrimidine_nucleoside phosphorylase activity in tumour and matched normal gastrointestinal mucosa Gut. 1982 Dec;23(12):1072-6._x000D_ 8: Kaspar F, Wolff DS, Neubauer P, Kurreck A, Arcus VL. pH-Independent Heat Capacity Changes during Phosphorolysis Catalyzed by the Pyrimidine_Nucleoside Phosphorylase from Geobacillus thermoglucosidasius Biochemistry. 2021 May 25;60(20):1573-1577._x000D_ 9: Liu G, Wang J, Chu J, Jiang T, Qin S, Gao Z, He B. Engineering Substrate Promiscuity of Nucleoside Phosphorylase Via an Insertions-Deletions Strategy JACS Au. 2024 Jan 13;4(2):454-464._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22475552">10: Vande Voorde J, Gago F, Vrancken K, Liekens S, Balzarini J. Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues Biochem J. 2012 Jul 1;445(1):113-23. </a>_x000D_ _x000D_ <strong>Products Related to Pyrimidine Nucleoside Phosphorylase can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>