Sulfo-Cyanine5.5 amine (potassium)

Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.

O=C(CCCCCN1C2=CC=C3C(C=C(S(=O)(O[K])=O)C=C3S(=O)(O[K])=O)=C2C(C)(C)/C1=C\C=C\C=C\C4=[N+](C)C5=C(C4(C)C)C(C=C(S(=O)(O)=O)C=C6S(=O)([O-])=O)=C6C=C5)NCCCCCCN

[1]Khatri S, et al.Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils. Bioconjugate Chemistry, 2019, 30(10), 2584-2593.