What is the catalog number for Nefiracetam?

The catalog number for Nefiracetam is HY-B0340.

What sizes are available for Nefiracetam?

Nefiracetam is available in the following size(s): 50 mg, 10 mM - 1 mL, 100 mg, 500 mg, 1 g.

How many pack sizes does Nefiracetam come in?

Nefiracetam is available in 5 different pack sizes.

Is Nefiracetam in stock?

Nefiracetam is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nefiracetam?

Nefiracetam is manufactured by QuantiMol.

What is the estimated delivery time for Nefiracetam?

Estimated delivery time for Nefiracetam is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nefiracetam?

The safety data sheet for Nefiracetam is available here: http://file.medchemexpress.com/batch_PDF/HY-B0340/Nefiracetam-SDS-MedChemExpress.pdf.

Nefiracetam

Nefiracetam is a cognition-enhancing agent. Nefiracetam is an activator of nAChR, N-methyl-D-aspartate receptor (NMDAR), mGluR5, PKC, gamma-aminobutyric acid (GABA), and N/L-type Ca2+ channels. Nefiracetam promotes neuroplasticity and enhances neuroprotection. Nefiracetam can be used in Alzheimer's disease, epilepsy, and cerebral ischemia research[1][2][3][4][5][6].

Product Specifications

CAS Number

77191-36-7

Product Name Alternative

DM9384; DZL-221

UNSPSC

12352005

Hazard Statement

H302

Target

Calcium Channel; GABA Receptor; iGluR; mGluR; nAChR; PKC

Type

Reference compound

Related Pathways

Epigenetics; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; TGF-beta/Smad

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nefiracetam.html

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 25 mg/mL

Smiles

O=C(NC1=C(C)C=CC=C1C)CN2C(CCC2)=O

Molecular Formula

C14H18N2O2

Molecular Weight

246.30

Precautions

H302

References & Citations

[1]Nomura T, et al. Nefiracetam facilitates hippocampal neurotransmission by a mechanism independent of the piracetam and aniracetam action. Brain Res. 2000 Jul 7;870 (1-2) :157-62.|[2]Moriguchi S, et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice. J Neurochem. 2009 Jul;110 (1) :170-81.|[3]Nishizaki T, et al. A 'long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam. Brain Res. 1999 May 1;826 (2) :281-8.|[4]Fukatsu T, et al. Effects of nefiracetam on spatial memory function and acetylcholine and GABA metabolism in microsphere-embolized rats. Eur J Pharmacol. 2002 Oct 18;453 (1) :59-67.|[5]Shiotani T, et al. Anticonvulsant actions of nefiracetam on epileptic EL mice and their relation to peripheral-type benzodiazepine receptors. Brain Res. 2000 Mar 24;859 (2) :255-61.|[6]Yoshii M, et al. Cellular mechanisms underlying cognition-enhancing actions of nefiracetam (DM-9384) . Behav Brain Res. 1997 Feb;83 (1-2) :185-8.